Analyze Publications Database

Integrity of normal-appearing white matter: Influence of age, visible lesion burden and hypertension in patients with small-vessel disease

Susana Muñoz Maniega1, Francesca M Chappell1, Maria C Valdés Hernández1, Paul A Armitage2, Stephen D Makin1, Anna K Heye1, Michael J Thrippleton1, Eleni Sakka1, Kirsten Shuler1, Martin S Dennis1, Joanna M Wardlaw1 . Integrity of normal-appearing white matter: Influence of age, visible lesion burden and hypertension in patients with small-vessel disease. J Cereb Blood Flow Metab. March 1st, 2016.

Publication Date
March 2016

How Analyze was Used
“generate binary masks of the WMH; index and any prior stroke lesions were identified by a neuroradiologist and excluded from the tissue masks manually by a trained image analyst, blind to all other information, using Analyze 11.0.”

Keywords
Magnetic resonance imaging
Cerebrovascular disease
Diffusion tensor imaging
Blood–brain barrier
Ageing

Author Affiliation(s)
1 Division of Neuroimaging Sciences, University of Edinburgh, Edinburgh, UK
2 Department of Cardiovascular Science, University of Sheffield, Sheffield, UK

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