Analyze Publications Database

Increased GABA levels in medial prefrontal cortex of young adults with narcolepsy

Kim SJ, Lyoo IK, Lee YS, Sung YH, Kim HJ, Kim JH, Kim KH, Jeong DU. Increased GABA levels in medial prefrontal cortex of young adults with narcolepsy. Sleep. March 2008;31(3):342-347.

Full Text – Open Access

Publication Date
March 2008

How Analyze was Used
“In the axial slice, which showed the most anterior boundary of the genu of corpus callosum, voxel (15×15×15 mm3) was placed closest to the genu of the corpus callosum and centered on the interhemispheric fissure. This voxel, which contains predominantly the bilateral anterior cingulate gray matter as previously described [Yamasue et al. 2002] was segmented into gray, white, and CSF using Analyze 5.”

Keywords
Adult
Basal Ganglia/physiopathology
Cataplexy/diagnosis/genetics/physiopathology
Female
Genotype
Glutamic Acid/metabolism
HLA-DQ Antigens/genetics
HLA-DQ beta-Chains
Humans
Magnetic Resonance Imaging (MRI)
Magnetic Resonance Spectroscopy
Male
Membrane Glycoproteins/genetics
Narcolepsy/diagnosis/genetics/physiopathology
Prefrontal Cortex/physiopathology
Reference Values
Sleep Disorders, Circadian Rhythm/diagnosis/genetics/physiopathology
gamma-Aminobutyric Acid/metabolism

Author Affiliation(s)
Department of Psychiatry, Gachon University of Medicine and Science, Incheon, South Korea. (SJK)

Sleep and Chronobiology Center, Seoul National University College of Medicine and Hospital, Seoul, South Korea. (ILK)

Department of Psychiatry, Seoul National University College of Medicine and Hospital, Seoul, South Korea. (IKL, HJK, JHK, KHK, DUJ)

Department of Psychiatry, Eunpyung Metropolitan Hospital, Seoul, South Korea. (YSL)

Department of Psychiatry, Harvard Medical School, McLean Hospital Brain Imaging Center, Belmont, MA, US. (YHS)

ID# 1633

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