Gray and white matter water diffusion in the syndromic variants of frontotemporal dementia

Whitwell JL, Avula R, Senjem ML, Kantarci K, Weigand SD, Samikoglu A, Edmonson HA, Vemuri P, Knopman DS, Boeve BF, Petersen RC, Josephs KA, Jack CR, Jr. Gray and white matter water diffusion in the syndromic variants of frontotemporal dementia. Neurology. April 2010;74(16):1279-1287.

Full Text – Open Access

Publication Date
April 2010

How Analyze was Used
“ROIs were placed on the tracts on the color-coded FA maps using ANALYZE software … by 1 rater (J.L.W.) blinded to clinical diagnosis.”

Keywords
Aged
Anisotropy
Atrophy/etiology/pathology/physiopathology
Brain/pathology/physiopathology
Brain Mapping
Case-Control Studies
Diffusion
Diffusion Tensor Imaging
Disease Progression
Female
Frontal Lobe/pathology/physiopathology
Frontotemporal Dementia/pathology/physiopathology
Frontotemporal Lobar Degeneration/pathology/physiopathology
Functional Laterality/physiology
Humans
Image Processing, Computer-Assisted
Male
Middle Aged
Nerve Fibers, Myelinated/pathology
Neural Pathways/pathology/physiopathology
Primary Progressive Nonfluent Aphasia/pathology/physiopathology
Severity of Illness Index
Temporal Lobe/pathology/physiopathology

Author Affiliation(s)
Departments of Radiology, Mayo Clinic Rochester, MN, US. (JLW, RA, KK, AS, HAE, PV, CRJ)

Information Technology, Mayo Clinic Rochester, MN, US. (MLS)

Biostatistics, Mayo Clinic Rochester, MN, US. (SDW)

Neurology (Behavioral Neurology), Mayo Clinic Rochester, MN, US. (DSK, BFB, RCP, KAJ)

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Gray and white matter water diffusion in the syndromic variants of frontotemporal dementia

Full Text – Open Access