Analyze Publications Database

Fatigue in Parkinson’s disease is linked to striatal and limbic serotonergic dysfunction

Pavese N, Metta V, Bose SK, Chaudhuri KR, Brooks DJ. Fatigue in Parkinson’s disease is linked to striatal and limbic serotonergic dysfunction. Brain. November 2010;133(11):3434-3443.

Full Text – Open Access

Publication Date
November 2010

How Analyze was Used
“After applying target regions to structures, 18F-dopa Ki and 11C-DASB BPND values were quantified using ANALYZE 8.1. 18F-dopa Ki and 11C-DASB BPND values obtained from the different regions of interest were averaged over both hemispheres for statistical analysis.”

Keywords
Adult
Aged
Corpus Striatum/metabolism/physiology
Fatigue/complications/metabolism/physiopathology
Female
Humans
Limbic System/metabolism/physiology
Male
Middle Aged
Parkinson Disease/complications/metabolism/physiopathology
Positron-Emission Tomography/methods
Serotonin/metabolism/physiology

Author Affiliation(s)
Department of Medicine, Centre for Neuroscience, Imperial College, London, UK. (NP, SKB, DJB)

Kings College and Lewisham Hospitals, Kings College, London, UK. (VM, KRC)

ID# 969

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