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Turner MR, Cagnin A, Turkheimer FE, Miller CC, Shaw CE, Brooks DJ, Leigh PN, Banati RB. Evidence of widespread cerebral microglial activation in amyotrophic lateral sclerosis: an [¹¹C](R)-PK11195 positron emission tomography study. Neurobiol Dis. April 2004;15(3):601-609.

Publication Date
April 2004

How Analyze was Used
“Volumes of interest (VOIs) were drawn bilaterally on consecutive slices of each individuals’ volumetric MRI, before co-registration with the respective PET image volume for blinding purposes (AnalyzeDirect Inc., Lenexa, KS).”

Keywords
Adult
Amyotrophic Lateral Sclerosis/metabolism/pathology/radionuclide imaging
Brain/metabolism/pathology/radionuclide imaging
Female
Humans
Isoquinolines/metabolism
Male
Microglia/metabolism/pathology
Middle Aged
Tomography, Emission-Computed

Author Affiliation(s)
Department of Neurology, Institute of Psychiatry, King’s College London, UK. (MRT, CCJM, CES, PNL)

MRC Clinical Sciences Centre and Division of Neuroscience, Imperial College, Hammersmith Hospital, London, UK. (MRT, FET, DJB, RBB)

Department of Neurology and Psychiatric Sciences, University of Padova, Italy. (AC)

Department of Neuropathology, Imperial College School of Medicine, Charing Cross Hospital, London W6 8RF, UK. (FET, RBB)

Institute of Neurology, London, UK. (DJB)

ID# 2189

Tags: Adult, Amyotrophic Lateral Sclerosis/metabolism/pathology/radionuclide imaging, Brain/metabolism/pathology/radionuclide imaging, Emission-Computed Tomography, Female, Humans, Isoquinolines/metabolism, Male, Microglia/metabolism/pathology, Middle Aged