AnalyzeDirect

Mach RH, Tu Z, Xu J, Li S, Jones LA, Taylor M, Luedtke RR, Derdeyn CP, Perlmutter JS, Mintun MA. Endogenous dopamine (DA) competes with the binding of a radiolabeled D³ receptor partial agonist in vivo: a positron emission tomography study. Synapse. August 2011;65(8):724-732.

Full Text – Open Access

Publication Date
August 2011

How Analyze was Used
“These images were then co-registered with MRI images to identify the regions of interest with Analyze software (AnalyzeDirect, Inc., Overland Park, KS).”

Keywords
Animals
Benzamides/chemical synthesis/pharmacokinetics
Binding, Competitive
Brain/metabolism/radionuclide imaging
Dopamine/pharmacokinetics
Dopamine Agonists/chemical synthesis/pharmacokinetics
Fluorine Radioisotopes/pharmacokinetics
Macaca mulatta
Male
Piperazines/chemical synthesis/pharmacokinetics
Positron-Emission Tomography
Radiopharmaceuticals/chemical synthesis/pharmacokinetics
Receptors, Dopamine D3/metabolism

Author Affiliation(s)
Division of Radiological Sciences, Washington University School of Medicine, Mallinckrodt Institute of Radiology, MO 63110, US. (RHM, ZT, JX, SL, LAJ, CPD, JSP, MAM)

Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, TX 76107, US. (MT, RRL)

ID# 688

Tags: Animals, Benzamides/chemical synthesis/pharmacokinetics, Brain/metabolism/radionuclide imaging, Competitive Binding, Dopamine Agonists/chemical synthesis/pharmacokinetics, Dopamine D3 Receptors/metabolism, Dopamine/pharmacokinetics, Fluorine Radioisotopes/pharmacokinetics, Macaca mulatta, Male, Piperazines/chemical synthesis/pharmacokinetics, Positron Emission Tomography (PET), Radiopharmaceuticals/chemical synthesis/pharmacokinetics