AnalyzeDirect Verhoeff NPLG, Petroff OAC, Hyder F, Zoghbi SS, Fujita M, Rajeevan N, Rothman DL, Seibyl JP, Mattson RH, Innis RB. Effects of vigabatrin on the GABAergic system as determined by [123I]iomazenil SPECT and GABA MRS. Epilepsia. October 1999;40(10):1433-1438.
Full Text – Open Access
Publication Date
October 1999
How Analyze was Used
“A rectangular VOI of 3 x 2 x 2 cm was drawn over the OC on the MRI and transferred to the SPECT by using the program ANALYZE 7.5.”
Keywords
Adult
Anticonvulsants/pharmacology
Female
Flumazenil/analogs & derivatives/diagnostic use
Humans
Iodine Radioisotopes/diagnostic use
Magnetic Resonance Spectroscopy/diagnostic use
Male
Middle Aged
Occipital Lobe/chemistry/drug effects/metabolism
Receptors, GABA/analysis/drug effects
Tomography, Emission-Computed, Single-Photon (SPECT)/statistics & numerical data
Vigabatrin/pharmacology
Author Affiliation(s)
Departments of Psychiatry, New Haven, and VA Connecticut Healthcare System, West Haven, CT, US. (NPLGV, SSZ, MF, NR, RBI)
Diagnostic Radiology, New Haven, and VA Connecticut Healthcare System, West Haven, CT, US. (OACP, FH, DLR, JPS)
Neurology, Yale University School of Medicine, New Haven, and VA Connecticut Healthcare System, West Haven, CT, US. (RHM)
ID# 2932
Tags: Adult, Anticonvulsants/pharmacology, Female, Flumazenil/analogs & derivatives/diagnostic use, GABA Receptors/analysis/drug effects, Humans, Iodine Radioisotopes/diagnostic use, Magnetic Resonance Spectroscopy/diagnostic use, Male, Middle Aged, Occipital Lobe/chemistry/drug effects/metabolism, Single-Photon Emission-Computed Tomography (SPECT)/statistics & numerical data, Vigabatrin/pharmacology