AnalyzeDirect

Davis SM, Donnan GA, Parsons MW, Levi C, Butcher KS, Peeters A, Barber PA, Bladin C, De Silva DA, Byrnes G, Chalk JB, Fink JN, Kimber TE, Schultz D, Hand PJ, Frayne J, Hankey G, Muir K, Gerraty R, Tress BM, Desmond PM. Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial. Lancet Neurol. April 2008;7(4):299-309.

Publication Date
April 2008

How Analyze was Used
“DWI at baseline and day 3–5 and T2-weighted lesions at day 90 were assessed by two independent raters who used standard planimetric software Analyze 7.0.”

Keywords
Aged
Aged, 80 and over
Double-Blind Method
Drug Evaluation
Echo-Planar Imaging/methods
Female
Fibrinolytic Agents/therapeutic use
Humans
Male
Middle Aged
Placebos
Prospective Studies
Retrospective Studies
Severity of Illness Index
Stroke/drug therapy/pathology
Thrombolytic Therapy/methods
Time Factors
Tissue Plasminogen Activator/therapeutic use
Treatment Outcome

Author Affiliation(s)
Department of Neurology, Royal Melbourne Hospital, University of Melbourne, Australia. (SMD, DADS, PJH)

Department of Radiology, Royal Melbourne Hospital, University of Melbourne, Australia. (BMT, PMD)

National Stroke Research Institute, Austin Health, University of Melbourne, Melbourne, Australia. (GAD)

Department of Public Health, University of Melbourne, Melbourne, Australia. (GB)

Hunter Medical Research Institute Centre for Brain and Mental Health Research, John Hunter Hospital, Newcastle, Australia. (MWP, CL)

Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada. (KSB)

University Hospital St Luc, Brussels, Belgium. (AP)

Neurology Department, Auckland City Hospital, Grafton, Auckland, New Zealand. (PAB)

Eastern Melbourne Neurosciences, Melbourne, Australia. (CB)

Royal Brisbane Hospital and Womens Hospital, Brisbane, Australia. (JBC)

Department of Medicine, Christchurch School of Medicine and Health Sciences, Christchurch, New Zealand. (JNF)

Royal Adelaide Hospital, Adelaide, Australia. (TEK)

Department of Neurology, Flinders Medical Centre, Bedford Park, Australia. (DS)

Cabrini Medical Centre, The Alfred Hospital, Malvern, Australia. (JF)

Royal Perth Hospital, Perth, Australia. (GH)

Division of Clinical Neuroscience, Section of Neurology, Southern General Hospital, Glasgow, UK. (KM)

The Alfred Hospital, East Melbourne, Australia. (RG)

ID# 1415

Tags: Aged, Aged_80 and over, Double-Blind Method, Drug Evaluation, Echo-Planar Imaging/methods, Female, Fibrinolytic Agents/therapeutic use, Humans, Male, Middle Aged, Placebos, Prospective Studies, Retrospective Studies, Severity of Illness Index, Stroke/drug therapy/pathology, Thrombolytic Therapy/methods, Time Factors, Tissue Plasminogen Activator/therapeutic use, Treatment Outcome