Analyze Publications Database

Effects of a 5-HT3 antagonist, ondansetron, on fasting and postprandial small bowel water content assessed by magnetic resonance imaging

Marciani L, Wright J, Foley S, Hoad CL, Totman JJ, Bush D, Hartley C, Armstrong A, Manby P, Blackshaw E, Perkins AC, Gowland PA, Spiller RC. Effects of a 5-HT3 antagonist, ondansetron, on fasting and postprandial small bowel water content assessed by magnetic resonance imaging. Aliment Pharmacol Ther. September 2010;32(5):655-663.

Full Text – Open Access

Publication Date
September 2010

How Analyze was Used
“Measurements of the volume of the gastric contents were carried out on the axial images by manually tracing a region of interest around the meal within the stomach on each image slice using Analyze 6 software … and summing across the slices to determine the total volume at different time points.”

Keywords
Adolescent
Adult
Aged
Diarrhea/drug therapy
Fasting
Female
Humans
Irritable Bowel Syndrome/drug therapy
Magnetic Resonance Imaging (MRI)
Male
Manometry
Middle Aged
Ondansetron/therapeutic use
Postprandial Period
Serotonin Antagonists/therapeutic use
Treatment Outcome
Young Adult

Author Affiliation(s)
Nottingham Digestive Diseases Centre and NIHR Biomedical Research Unit, Queen’s Medical Centre Campus, Nottingham University Hospitals NHS Trust, University of Nottingham, Nottingham, UK. (LM, JW, SF, DB, CH, AA, PM, EB, ACP, RCS)

Sir Peter Mansfield Magnetic Resonance Centre, University of Nottingham, Nottingham, UK. (CLH, PAG)

Brain and Body Centre, University of Nottingham, Nottingham, UK. (JJT)

ID# 1145

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