AnalyzeDirect Coleman NS, Marciani L, Blackshaw E, Wright J, Parker M, Yano T, Yamazaki S, Chan PQ, Wilde K, Gowland PA, Perkins AC, Spiller RC. Effect of a novel 5-HT3 receptor agonist MKC-733 on upper gastrointestinal motility in humans. Aliment Pharmacol Ther. November 2003;18(10):1039-1048.
Full Text – Open Access
Publication Date
November 2003
How Analyze was Used
“A region of interest was drawn around the gastric contents on each image (Analy[z]e software …). The volume of the gastric contents was calculated by summing the areas across the slices.”
Keywords
Adolescent
Adult
Body Mass Index
Cross-Over Studies
Double-Blind Method
Gamma Cameras
Gastrointestinal Motility/drug effects
Humans
Magnetic Resonance Imaging (MRI)/methods
Male
Manometry
Middle Aged
Pyridines/pharmacology
Quinuclidines/pharmacology
Serotonin 5-HT3 Receptor Agonists
Serotonin Receptor Agonists/pharmacology
Stomach/radionuclide imaging
Author Affiliation(s)
Division of Gastroenterology, School of Medical and Surgical Sciences, University Hospital, Nottingham, UK. (NSC, RCS)
Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, UK. (LM, PAG)
Department of Medical Physics, University Hospital, Nottingham, UK. (EB, ACP)
Division of Surgery, School of Medical and Surgical Sciences, University Hospital, Nottingham, UK. (JW, MP)
Mitsubishi Pharma Europe Ltd, London, UK. (PQC, KW)
Pharmaceuticals Research Unit, Research and Development Division, Mitsubishi Pharma Corporation, Kamoshida-cho, Aoba-ku, Yokohama, Japan. (TY, SY)
ID# 2445
Tags: Adolescent, Adult, Body Mass Index, Cross-Over Studies, Double-Blind Method, Gamma Cameras, Gastrointestinal Motility/drug effects, Humans, Magnetic Resonance Imaging (MRI)/methods, Male, Manometry, Middle Aged, Pyridines/pharmacology, Quinuclidines/pharmacology, Serotonin 5-HT3 Receptor Agonists, Serotonin Receptor Agonists/pharmacology, Stomach/radionuclide imaging