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Early Perihematomal Edema Expansion: Definition, Significance, and Association with Outcomes after Intracerebral Hemorrhage

Xin-Ni Lv et al. Early Perihematomal Edema Expansion: Definition, Significance, and Association with Outcomes after Intracerebral Hemorrhage Oxidative Medicine and Cellular Longevity.

Publication Date
September 13, 2021

How Analyze was Used
“ICH and PHE volumes on admission and follow-up CT scans were segmented by a semiautomated computer-assisted volumetric analysis as previously described (Version 11.0; AnalyzeDirect, Overland Park, KS, USA). In brief, the PHE volume was measured slice by slice on both baseline and follow-up CT scans. All images were evaluated independently by two experienced neurologists in a blinded manner. Hematoma expansion was defined as an increase in hematoma volume of >33% or >6 mL at follow-up CT scan. A semiautomated threshold-based approach (range of 5–33 Hounsfield Units) was applied to identify edematous regions as previously described.”

Keywords
Perihematomal edema, Intracerebral hemorrhage, Functional outcome, Computed tomography

Author Affiliation(s)
The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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