AnalyzeDirect Spinelli S, Chefer S, Suomi SJ, Higley JD, Barr CS, Stein E. Early-life stress induces long-term morphologic changes in primate brain. Arch Gen Psychiatry. June 2009;66(6):658-665.
Full Text – Open Access
Publication Date
June 2009
How Analyze was Used
“Image processing was performed with Analyze 7.5 … For manual tracings of the regions of interest (ROIs), T1-weighted images were converted to cubic voxel dimensions of 0.39 mm. All images were oriented in a standardized oblique plane to eliminate any bias in section angle. In the standardized orientation, the transaxial plane was parallel to the anteroposterior commissures line and perpendicular to the interhemispheric fissure.”
Keywords
Age Factors
Animals
Brain/pathology
Cerebellum/pathology
Corpus Callosum/pathology
Dominance, Cerebral/physiology
Female
Gyrus Cinguli/pathology
Hippocampus/pathology
Hydrocortisone/blood
Hydroxyindoleacetic Acid/blood
Image Processing, Computer-Assisted
Macaca mulatta
Magnetic Resonance Imaging (MRI)
Male
Maternal Deprivation
Prefrontal Cortex/physiology
Reference Values
Social Environment
Statistics as Topic
Stress Disorders, Post-Traumatic/pathology
Author Affiliation(s)
Laboratory of Clinical and Translational Studies, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health and Human Services, Bethesda, MD, US. (SS, CSB)
Neuroimaging Research Branch, National Institute on Drug Abuse, National Institutes of Health and Human Services, Bethesda, MD, US. (SC, ES)
Laboratory of Comparative Ethology, National Institute of Child Health and Human Development, National Institutes of Health and Human Services, Bethesda, MD, US. (SJS)
Department of Psychology, Brigham Young University, Provo, UT, US. (JDH).
ID# 1322
Tags: Age Factors, Animals, Brain/pathology, Cerebellum/pathology, Cerebral Dominance/physiology, Computer-Assisted Image Processing, Corpus Callosum/pathology, Female, Gyrus Cinguli/pathology, Hippocampus/pathology, Hydrocortisone/blood, Hydroxyindoleacetic Acid/blood, Macaca mulatta, Magnetic Resonance Imaging (MRI), Male, Maternal Deprivation, Post-Traumatic Stress Disorders/pathology, Prefrontal Cortex/physiology, Reference Values, Social Environment, Statistics as Topic