AnalyzeDirect Jackowski A, Perera TD, Abdallah CG, Garrido G, Tang CY, Martinez J, Mathew SJ, Gorman JM, Rosenblum LA, Smith ELP, Dwork AJ, Shungu DC, Kaffman A, Gelernter J, Coplan JD, Kaufman J. Early-life stress, corpus callosum development, hippocampal volumetrics, and anxious behavior in male nonhuman primates. Psychiatry Res. April 2011;192(1):37-44.
Full Text – Open Access
Publication Date
April 2011
How Analyze was Used
“The axial MPRAGE series were imported into ANALYZE AVW 7.0 software platform. In order to isolate whole brain from its surroundings, skull, surface CSF, and meninges were stripped using a combination of tools including image thresholding, region growing, and manual tracing.”
Keywords
Analysis of Variance
Animals
Anxiety/pathology/physiopathology
Behavior, Animal
Brain Mapping
Corpus Callosum/growth & development/pathology/physiopathology
Cross-Sectional Studies
Fear
Gene Frequency
Genotype
Hippocampus/growth & development/pathology/physiopathology
Image Processing, Computer-Assisted
Linear Models
Macaca radiata
Magnetic Resonance Imaging (MRI)
Male
Serotonin Plasma Membrane Transport Proteins/genetics
Stress, Psychological/pathology/physiopathology
Author Affiliation(s)
LiNC, Departamento de Psiquiatria, Universidade Federal de São Paulo, SP, Brazil. (AJ)
Department of Biological Psychiatry, New York State Psychiatric Institute, College of Physicians and Surgeons of Columbia University, New York, NY, US. (TDP, AJD, JDC)
Nonhuman Primate Facility, Department of Psychiatry, SUNY Downstate Medical Center, Brooklyn, NY, US. (CGA, LAR, ELPS, JDC)
Serviço de Informática Médica, Instituto do Coração, Universidade de São Paulo, SP, Brazil. (GG)
Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, US. (CYT, HM)
Comprehensive NeuroScience Inc., White Plains, NY, US. (JMG)
Department of Molecular Imaging and Neuropathology, New York State Psychiatric Institute, New York, NY, US. (AJD)
Department of Pathology and Cell Biology, College of Physicians and Surgeons of Columbia University, New York, NY, US. (AJD)
Department of Radiology, Weill Medical College of Cornell University, New York, NY, US. (DKS)
Department of Psychiatry, Weill Medical College of Cornell University, New York, NY, US. (DKS)
Department of Biophysics, Weill Medical College of Cornell University, New York, NY, US. (DKS)
Division of Human Genetics (Psychiatry), Yale University School of Medicine, New Haven, CT, US. (JG)
Department of Psychiatry, Yale University School of Medicine, New Haven, CT, US. (AK, JG, JK)
Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, US. (SJM)
ID# 949
Tags: Analysis of Variance, Animal Behavior, Animals, Anxiety/pathology/physiopathology, Brain Mapping, Computer-Assisted Image Processing, Corpus Callosum/growth & development/pathology/physiopathology, Cross Sectional Studies, Fear, Gene Frequency, Genotype, Hippocampus/growth & development/pathology/physiopathology, Linear Models, Macaca radiata, Magnetic Resonance Imaging (MRI), Male, Psychological Stress/pathology/physiopathology, Serotonin Plasma Membrane Transport Proteins/genetics