Analyze Publications Database

Early emphysematous changes in asymptomatic smokers: detection with 3He MR imaging

Fain SB, Panth SR, Evans MD, Wentland AL, Holmes JH, Korosec FR, O’Brien MJ, Fountaine H, Grist TM. Early emphysematous changes in asymptomatic smokers: detection with 3He MR imaging. Radiology. June 2006;239(3):875-883.

Full Text – Open Access

Publication Date
June 2006

How Analyze was Used
“The RA950 was calculated by using the full-inspiration breath-hold data for each section by using tools in a software package (Analyze …), with application of the following procedures: (a) Manual segmentation of the right and left lungs from the chest wall and back was performed by an image scientist with 2 years of experience (A.L.W.). (b) Threshold limits were applied to the segmented image to include only voxels within the range of −1024 to −950 HU. (c) The ratio of the area of the threshold image to that of the entire area of the segmented right and left lungs for each section was then calculated.”

Keywords
Adolescent
Adult
Age Factors
Aged
Carbon Monoxide/diagnostic use
Diffusion Magnetic Resonance Imaging/methods
Early Diagnosis
Female
Forced Expiratory Volume/physiology
Helium
Humans
Image Processing, Computer-Assisted/methods
Isotopes
Lung/physiopathology
Male
Middle Aged
Prospective Studies
Pulmonary Diffusing Capacity/physiology
Pulmonary Emphysema/diagnosis/physiopathology
Smoking/physiopathology
Spirometry
Tomography, X-Ray Computed/methods
Vital Capacity/physiology

Author Affiliation(s)
Department of Radiology, University of Wisconsin, J3/110 CSC Medical Physics, 600 Highland Ave, Madison, WI 53792, US. (SBF, FRK, TMG)

Department of Medical Physics, University of Wisconsin, J3/110 CSC Medical Physics, 600 Highland Ave, Madison, WI 53792, US. (SBF, JHH, TMG)

Department of Biomedical Engineering, University of Wisconsin, J3/110 CSC Medical Physics, 600 Highland Ave, Madison, WI 53792, US. (SBF, SRP, ALW, TMG)

Department of Biostatistics and Medical Informatics, University of Wisconsin, J3/110 CSC Medical Physics, 600 Highland Ave, Madison, WI 53792, US. (MDE)

Department of Pulmonary Function, University of Wisconsin, J3/110 CSC Medical Physics, 600 Highland Ave, Madison, WI 53792, US. (MJO)

GE Healthcare, Princeton, NJ, US. (HF)

ID# 1923

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