Analyze Publications Database

Does induced hypertension reduce cerebral ischaemia within the traumatized human brain?

Coles JP, Steiner LA, Johnston AJ, Fryer TD, Coleman MR, Smieleweski P, Chatfield DA, Aigbirhio F, Williams GB, Boniface S, Rice K, Clark JC, Pickard JD, Menon DK. Does induced hypertension reduce cerebral ischaemia within the traumatized human brain? Brain. November 2004;127(Pt 11):2479-2490.

Full Text – Open Access

Publication Date
November 2004

How Analyze was Used
“Images were analysed using custom-designed automated software [Petan (Smielewski et al., 2002)] incorporating elements of Statistical Parametric Mapping …, Matlab 5.2 … , Analyze 4.0 (AnalyzeDirect, Lenexa, KA, USA)] and co-registration by multiresolution optimization of mutual information.”

Keywords
Adolescent
Adult
Aged
Brain Ischemia/etiology/prevention & control
Cerebrovascular Circulation
Craniocerebral Trauma/complications/physiopathology/therapy
Electroencephalography
Female
Humans
Image Processing, Computer-Assisted/methods
Intracranial Hypertension/etiology/physiopathology
Linear Models
Male
Middle Aged
Norepinephrine/therapeutic use
Oxygen Consumption
Positron-Emission Tomography (PET)
Vasoconstrictor Agents/therapeutic use

Author Affiliation(s)
Division of Anaesthesia, University of Cambridge, Cambridge, UK. (JPC, AJJ, DAC, DKM)

Wolfson Brain Imaging Centre,University of Cambridge, Cambridge, UK. (JPC, LAS, AJJ, TDF, MRC, PS, DAC, FA, GBW, SB, JCC, JDP, DKM)

Department of Neurosurgery, University of Cambridge, Cambridge, UK. (LAS, PS, JDP)

Department of Clinical Neurophysiology, Addenbrooke’s Hospital, Cambridge, UK. (MRC, SB)

Medical Research Council Biostatistics Unit, Institute of Public Health, Cambridge, UK. (KR)

ID# 2184

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