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Yancy AD, Olzinski AR, Hu TCC, Lenhard SC, Aravindhan K, Gruver SM, Jacobs PM, Willette RN, Jucker BM. Differential uptake of ferumoxtran-10 and ferumoxytol, ultrasmall superparamagnetic iron oxide contrast agents in rabbit: critical determinants of atherosclerotic plaque labeling. J Magn Reson Imaging. April 2005;21(4):432-442.

Publication Date
April 2005

How Analyze was Used
“The ex vivo gradient echo images were analyzed on a Silicon Graphics O 2 Workstation … using Analyze AVW software package (AnalyzeDirect, Lenexa, KS, USA).”

Keywords
Animals
Arteriosclerosis/diagnosis/metabolism
Contrast Media/pharmacokinetics
Dextrans
Ferrosoferric Oxide
Iron/pharmacokinetics
Macrophages/metabolism/pathology
Magnetic Resonance Imaging (MRI)
Magnetite Nanoparticles
Male
Oxides/pharmacokinetics
Rabbits

Author Affiliation(s)
Laboratory Animal Sciences, GlaxoSmithKline, King of Prussia, PA, US. (ADY)

Investigative and Cardiac Biology, Cardiovascular and Urogenital Center of Excellence in Drug Discovery, GlaxoSmithKline, King of Prussia, PA, US. (ARO, TCCH, SCL, KA, SMG, RNW, BMJ)

Advanced Magnetics, Inc., Cambridge, MA, US. (PMJ)

ID# 2102

Tags: Animals, Arteriosclerosis/diagnosis/metabolism, Contrast Media/pharmacokinetics, Dextrans, Ferrosoferric Oxide, Iron/pharmacokinetics, Macrophages/metabolism/pathology, Magnetic Resonance Imaging (MRI), Magnetite Nanoparticles, Male, Oxides/pharmacokinetics, Rabbits