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Developing consistently reproducible intervertebral disc degeneration at rat caudal spine by using needle puncture: laboratory investigation

Zhang H, La Marca F, Hollister SJ, Goldstein SA, Lin C-Y. Developing consistently reproducible intervertebral disc degeneration at rat caudal spine by using needle puncture: laboratory investigation. J Neurosurg Spine. June 2009;10(6):522-530.

Publication Date
June 2009

How Analyze was Used
“All 8 of the T2-weighted midsagittal images of the discs in the intact and stabbed groups were analyzed qualitatively to track the degeneration progress. Quantitative analysis of the image slices was processed using Analyze 7.0 (AnalyzeDirect).”

Keywords
Bone Morphogenetic Protein Receptor Type II
Caudal Spine
Intervertebral Disc Degeneration
Needle Puncture
Stab Injury
Rat

Author Affiliation(s)
Spine Research Laboratory, Department of Neurosurgery, University of Michigan Medical School, Ann Arbor, Michigan. (HZ, FLM, SJH, C-YL)

Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan. (HZ, SJH, SAG, C-YL)

Orthopaedic Research Laboratories, Department of Orthopaedic Surgery, University of Michigan Medical School, Ann Arbor, Michigan. (SAG)

ID# 1208

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