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Determination of critical-sized defect of mandible in a rabbit model: Micro-computed tomography, and histological evaluation

Yue Wang et al. Determination of critical-sized defect of mandible in a rabbit model: Micro-computed tomography, and histological evaluation Heliyon.

Publication Date
July 16, 2023

How Analyze was Used
“To compare the bone reconstruction, samples were analysed using PerkinElmer Quantum GX (Micro-CT, PerkinElmer, USA) with the following parameters: voltage, 90 kV; current, 88 μA; field of view, 36 mm; and resolution, 72 μm/pixel. Caliper Micro-CT Analysis Tools (Caliper, USA) in the Analyze software were used for processing and visualization of 3D images. The region of interest was defined as a regular cuboid with 1 mm length, 2 mm width, and 1 mm height. The bone volume to total volume ratio (BV/TV) of the bone tissue in the rabbit jaw bone defect was calculated, expressed as the percentage of new bone formation, and analysed statistically.”

Keywords
Rabbit, Laboratory animal, Mandibular defect, Bone loss, Critical-sized defect

Author Affiliation(s)
Hebei Clinical Research Center for Oral Diseases, Shijiazhuang, China

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