Analyze Publications Database

Detection of early changes in the post-radiosurgery vestibular schwannoma microenvironment using multinuclear MRI

Daniel Lewis et al. Detection of early changes in the post-radiosurgery vestibular schwannoma microenvironment using multinuclear MRI Scientific Reports.

Publication Date
August 3, 2021

How Analyze was Used
“To allow accurate comparison of longitudinal changes in imaging parameters (TSC, diffusion metrics and DCE-MRI derived microvascular parameters) in each tumour ROI and across each tumour voxel, individual tumours were manually delineated on the co-registered pre-treatment T1W post-contrast image using Analyze version 11 (Biomedical Imaging Resource, Mayo Clinic, Rochester, MN, USA) to create a tumour object mask. These object masks, defined on the pre-treatment T1W post-contrast image for each patient, were then applied to the co-registered TSC maps, DCE-MRI microvascular kinetic parameter maps and the diffusion parameter maps (MD, FA).”

Keywords
Cancer imaging, Cancer microenvironment, CNS cancer, Predictive markers, Translational research, Tumour biomarkers

Author Affiliation(s)
Wolfson Molecular Imaging Centre (WMIC), University of Manchester, Manchester, UK

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