AnalyzeDirect Maks CB, Butson CR, Walter BL, Vitek JL, McIntyre CC. Deep brain stimulation activation volumes and their association with neurophysiological mapping and therapeutic outcomes. J Neurol Neurosurg Psychiatry. June 2009;80(6):659-666.
Full Text – Open Access
Publication Date
June 2009
How Analyze was Used
“Each patient underwent pre-operative computed tomography (CT) and/or magnetic resonance imaging (MRI) as part of the standard DBS surgical protocol.”
“Each image co-registration was performed using Analyze 7.0 (AnalyzeDirect, Lenexa, KS, USA). We used the ITK 3D-registration function in Analyze, followed by manual adjustment to precisely match the positions of the anterior and posterior commissures. Co-registrations involving two or more data sets from the same patient required only rotation and translation to yield near-perfect overlaps.”
Keywords
Brain Mapping/methods
Deep Brain Stimulation/methods
Diffusion Magnetic Resonance Imaging/methods
Dominance, Cerebral/physiology
Electrodes, Implanted
Humans
Image Processing, Computer-Assisted/methods
Imaging, Three-Dimensional
Magnetic Resonance Imaging (MRI)/methods
Nerve Net/physiopathology
Neurologic Examination
Neurons/physiology
Parkinson Disease/physiopathology/therapy
Substantia Nigra/physiopathology
Subthalamic Nucleus/physiopathology
Synaptic Transmission/physiology
Thalamus/physiopathology
Tomography, X-Ray Computed/methods
Treatment Outcome
Author Affiliation(s)
Department of Biomedical Engineering, Cleveland Clinic Foundation, Cleveland, Ohio, US. (CBM, CRB, CCM)
Center for Neurological Restoration, Cleveland Clinic Foundation, Cleveland, Ohio, US. (BLW, JLV, CCM)
Department of Neurosciences, Cleveland Clinic Foundation, Cleveland, Ohio, US. (JLV)
ID# 1209
Tags: Brain Mapping/methods, Cerebral Dominance/physiology, Computer-Assisted Image Processing/methods, Deep Brain Stimulation/methods, Diffusion Magnetic Resonance Imaging/methods, Humans, Implanted Electrodes, Magnetic Resonance Imaging (MRI)/methods, Nerve Net/physiopathology, Neurologic Examination, Neurons/physiology, Parkinson Disease/physiopathology/therapy, Substantia Nigra/physiopathology, Subthalamic Nucleus/physiopathology, Synaptic Transmission/physiologyThalamus/physiopathology, Three-Dimensional Imaging, Treatment Outcome, X-Ray Computed Tomography/methods