AnalyzeDirect Hessl D, Wang JM, Schneider A, Koldewyn K, Le L, Iwahashi C, Cheung K, Tassone F, Hagerman PJ, Rivera SM. Decreased fragile X mental retardation protein expression underlies amygdala dysfunction in carriers of the fragile X premutation. Biol Psychiatry. November 2011;70(9):859-865.
Full Text – Open Access
Publication Date
November 2011
How Analyze was Used
“Amygdala volumes were quantified by operator-guided manual segmentations using…Analyze 8.5 and 9.0 [Robb 2001, Robb and Barillot 1989, Robb et al. 1989].”
Keywords
Adult
Amygdala/pathology
Autistic Disorder/diagnosis/genetics/pathology
Brain/pathology
Cognition/physiology
DNA/genetics
Emotions/physiology
Eye Movements/physiology
Fragile X Mental Retardation Protein/biosynthesis/genetics
Heterozygote
Humans
Image Processing, Computer-Assisted
Intelligence Tests
Magnetic Resonance Imaging
Male
Mutation/genetics
Neuropsychological Tests
Psychomotor Performance/physiology
RNA, Messenger/biosynthesis/genetics
Author Affiliation(s)
Medical Investigation of Neurodevelopmental Disorders (M.I.N.D.) Institute, University of California-Davis, Medical Center, Sacramento, CA, US. (DH, AS, FT, PJH, SMR)
Departments of Psychiatry and Behavioral Sciences, University of California-Davis, Medical Center, Sacramento, CA, US. (DH, AS)
Department of Biochemistry and Molecular Medicine, University of California-Davis, School of Medicine, Davis, CA, US. (CI, KC, FT, PJH)
Department of Psychology, University of California-Davis, Davis, CA, US. (SMR)
Center for Mind and Brain, University of California-Davis, Davis, CA, US. (JMW, LL, SMR)
Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, US. (KK)
McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA, US. (KK)
ID# 663
Tags: Adult, Amygdala/pathology, Autistic Disorder/diagnosis/genetics/pathology, Brain/pathology, Cognition/physiology, Computer-Assisted Image Processing, DNA/genetics, Emotions/physiology, Eye Movements/physiology, Fragile X Mental Retardation Protein/biosynthesis/genetics, Heterozygote, Humans, Intelligence Tests, Magnetic Resonance Imaging (MRI), Male, Messenger RNA/biosynthesis/genetics, Mutation/genetics, Neuropsychological Tests, Psychomotor Performance/physiology