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Copper-64-pyruvaldehyde-bis(N4-methylthiosemicarbazone) for the prevention of tumor growth at wound sites following laparoscopic surgery: monitoring therapy response with microPET and magnetic resonance imaging

Lewis JS, Connett JM, Garbow JR, Buettner TL, Fujibayashi Y, Fleshman JW, Welch MJ. Copper-64-pyruvaldehyde-bis(N4-methylthiosemicarbazone) for the prevention of tumor growth at wound sites following laparoscopic surgery: monitoring therapy response with microPET and magnetic resonance imaging. Cancer Res. January 2002;62(2):445-449.

Full Text – Open Access

Publication Date
January 2002

How Analyze was Used
“Tumor volume from the microPET images was determined using AnalyzeAVW 3.0.”

Keywords
Abdominal Muscles/pathology
Abdominal Neoplasms/metabolism/prevention & control/radionuclide
imaging/secondary
Animals
Cell Division/drug effects
Colonic Neoplasms/metabolism/pathology/radionuclide imaging/therapy
Copper Radioisotopes/diagnostic use
Cricetinae
Laparoscopy/adverse effects
Magnetic Resonance Imaging (MRI)
Mesocricetus
Neoplasm Seeding
Organometallic Compounds/pharmacokinetics/pharmacology
Radiopharmaceuticals/diagnostic use/pharmacokinetics/pharmacology
Thiosemicarbazones/pharmacokinetics/pharmacology
Tissue Distribution
Tomography, Emission-Computed
Xenograft Model Antitumor Assays

Author Affiliation(s)
Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110, US. (JSL, MJW)

Department of Surgery, Washington University School of Medicine, St. Louis, MO 63110, US. (JMC, TLB, JWF)

Department of Chemistry, Washington University, St. Louis, MO 63110, US. (JRG)

Biomedical Imaging Research Center, Fukui Medical University, Matsuoka, Fukui 910-1193, Japan. (YF)

ID# 2557

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