AnalyzeDirect Allison Buchanan1, Ruben Cohen2, Stephen Looney3,4, Sajitha Kalathingal1, Scott De Rossi5. Cone-beam CT analysis of patients with obstructive sleep apnea compared to normal controls. Imaging Science in Dentistry. March 24th, 2016.
Full Text – Open Access
Publication Date
March 2016
How Analyze was Used
“The CBCT images were exported as DICOM (.dcm) files and then imported into the software program Analyze 10.0 (AnalyzeDirect, Overland Park, KS, USA) for analysis of the airway. […] The upper airway affected by OSA is frequently defined as the soft tissue region bounded by the nasopharynx superiorly and the epiglottis inferiorly. Therefore, the oropharynx from hard palate to epiglottis was isolated from the data for analysis by manual segmentation of each axial slice from the surrounding soft tissue using thresholding, or setting the upper and lower grey level values of the area of interest (upper airway). […] Once the airway was isolated, the software computed the area (mm2) and volume (mm3) of each axial slice for the entire isolated portion of the airway. These area and volume measurements were used to identify the smallest axial slice, and width and anterior-posterior (A-P) dimension measurements were then carried out on the smallest axial slice in each CBCT study. The average of multiple measurements was recorded as the value representing the width and AP dimension. […] The total number of axial slices segmented from the hard palate to the epiglottis were used to calculate the airway length.”
Keywords
Cone-Beam Computed Tomography
Humans
Prospective Studies
Retrospective Studies
Sleep Apnea Syndromes
Sleep Apnea, Obstructive
Author Affiliation(s)
1Division of Radiology, Department of Oral Health and Diagnostic Sciences, Dental College of Georgia, Augusta University, Augusta, GA, USA.
2Park Avenue Oral and Facial Surgery, New York, NY, USA.
3Department of Biostatistics and Epidemiology, Augusta University Medical College of Georgia, Augusta, GA, USA.
4Department of Oral Health and Diagnostic Sciences, Georgia Regents University, Dental College of Georgia, Augusta, GA, USA.
5Division of Oral Medicine, Department of Oral Health and Diagnostic Sciences, Dental College of Georgia, Augusta University, Augusta, GA, USA.