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Comparison of [11C]TZ1964B and [18F]MNI659 for PET imaging brain PDE10A in nonhuman primates

Hui Liu1, Hongjun Jin1, Xuyi Yue1, Junbin Han1, Hao Yang1, Hubert Flores1, Yi Su1, David Alagille2, Joel S. Perlmutter1,3,4, Gilles Tamagnan2, Zhude Tu1. Comparison of [11C]TZ1964B and [18F]MNI659 for PET imaging brain PDE10A in nonhuman primates. Pharmacology Research & Perspectives. August 26 2016.

Full Text – Open Access

Publication Date
August 2016

How Analyze was Used
“The reconstructed PET images were co-registered…and superimposed using Analyze 10.0 (AnalyzeDirect, Overland Park, KS) for quality control.”

Keywords
Nonhuman primates, PDE10A, PET radiotracer, Tracer kinetics, Tracer metabolism, Tracer uptake

Author Affiliation(s)

1 Department of Radiology, Washington University School of Medicine, St. Louis, Missouri
2 Molecular NeuroImaging, LLC, New Haven, Connecticut
3 Department of Neurology, Washington University School of Medicine, St. Louis, Missouri
4 Department of Neuroscience, Physical Therapy and Occupational Therapy, Washington University School of Medicine, St. Louis, Missouri

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