Analyze Publications Database

Combining RASG12C(ON) inhibitor with SHP2 inhibition sensitises immune excluded lung tumours to immune checkpoint blockade: a strategy for turning cold tumours hot

Panayiotis Anastasiou et al. Combining RASG12C(ON) inhibitor with SHP2 inhibition sensitises immune excluded lung tumours to immune checkpoint blockade: a strategy for turning cold tumours hot bioRxiv.

Publication Date
January 16, 2024

How Analyze was Used
“Tumour volume was measured by micro-CT analysis. Mice were anaesthetised by inhalation of isoflurane and scanned using the Quantum GX2 micro-CT imaging system (Perkin Elmer). Serial lung images were reconstructed and tumour volumes analysed using Analyse (AnalyzeDirect) as previously described.”

Keywords
Lung tumours, Lung cancer, Cancer biology

Author Affiliation(s)
Francis Crick Institute, London, United Kingdom

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