Analyze Publications Database

Combined contrast-enhanced ultrasound and rt-PA treatment is safe and improves impaired microcirculation after reperfusion of middle cerebral artery occlusion

Nedelmann M, Ritschel N, Doenges S, Langheinrich AC, Acker T, Reuter P, Yeniguen M, Pukropski J, Kaps M, Mueller C, Bachmann G, Gerriets T. Combined contrast-enhanced ultrasound and rt-PA treatment is safe and improves impaired microcirculation after reperfusion of middle cerebral artery occlusion. J Cereb Blood Flow Metab. October 2010;30(10):1712-1720.

Full Text – Open Access

Publication Date
October 2010

How Analyze was Used
“The X-ray system is based on a microfocus tube (20 to 80 kVp, 0 to 100 μA) reaching a minimum spot size of 8 μm at 8 W generating projection images irradiating X-rays in cone-beam geometry….The resulting 3D images were displayed using Analyze 8.0.”

Keywords
Animals
Contrast Media/therapeutic use
Fibrinolytic Agents/therapeutic use
Infarction, Middle Cerebral Artery/drug therapy/pathology
Magnetic Resonance Imaging (MRI)
Male
Microcirculation/drug effects
Rats
Rats, Wistar
Reperfusion
Stroke/drug therapy/pathology
Thrombolytic Therapy/methods
Tissue Plasminogen Activator/therapeutic use
Ultrasonography/methods

Author Affiliation(s)
Department of Neurology, Justus Liebig University, Giessen, Germany. (MN, SD, PR, MY, MK, TG)

Department of Experimental Neurology, Justus Liebig University, Giessen and Kerckhoff Clinic, Bad Nauheim, Germany. (MN, SD, PR, JP, CM, CB, TG)

Max-Planck-Institute for Heart and Lung Research, Bad Nauheim, Germany. (NR)

Department of Radiology, Justus Liebig University, Giessen, Germany. (ACL)

Institute of Neuropathology, Justus Liebig University, Giessen, Germany. (TA)

ID# 1079

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