AnalyzeDirect Smith ME, Stone LA, Albert PS, Frank JA, Martin R, Armstrong M, Maloni H, McFarlin DE, McFarland HF. Clinical worsening in multiple sclerosis is associated with increased frequency and area of gadopentetate dimeglumine-enhancing magnetic resonance imaging lesions. Ann Neurol. May 1993;33(5):480-489.
Publication Date
May 1993
How Analyze was Used
“For lesion area determination, the scans were transferred to a Sun workstation. Using the Analyze 5.0.1 software …, areas of the total number of enhancing lesions on each scan slice were measured in pixels (single volume picture elements).”
Keywords
Adult
Brain/pathology
Gadolinium/diagnostic use
Gadolinium DTPA
Humans
Magnetic Resonance Imaging (MRI)/methods
Methylprednisolone/therapeutic use
Middle Aged
Multiple Sclerosis/drug therapy/pathology/physiopathology
Organometallic Compounds/diagnostic use
Pentetic Acid/diagnostic use
Prednisone/therapeutic use
Recurrence
Remission, Spontaneous
Spine/pathology
Time Factors
Visual Acuity
Author Affiliation(s)
Neuroimmunology Branch, National Institutes of Health, Bethesda, MD, US. (MES, LAS, HM, DEF, HFM)
Biometry and Field Studies Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD US. (PSA)
The Diagnostic Radiology Research Program National Institutes of Health, Bethesda, MD US. (JAF)
Clincial Center, Diagnostic Radiology Department, National Institutes of Health, Bethesda, MD US. (RM)
The Department of Neurology, University of Tubingen, Tubingen, Germany. (MA)
ID# 3101
Tags: Adult, Brain/pathology, Gadolinium DTPA, Gadolinium/diagnostic use, Humans, Magnetic Resonance Imaging (MRI)/methods, Methylprednisolone/therapeutic use, Middle Aged, Multiple Sclerosis/drug therapy/pathology/physiopathology, Organometallic Compounds/diagnostic use, Pentetic Acid/diagnostic use, Prednisone/therapeutic use, Recurrence, Spine/pathology, Spontaneous Remission, Time Factors, Visual Acuity