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Chronic lead exposure induces fatty liver disease associated with the variations of gut microbiota

Heng Wan et al. Chronic lead exposure induces fatty liver disease associated with the variations of gut microbiota Ecotoxicology and Environmental Safety.

Publication Date
January 29, 2022

How Analyze was Used
“At the last week of the experiment, the rats were anesthetized with isoflurane gas (5% induction, 3% maintenance) for quantifying the visceral fat volume using micro-CT imaging (Quantum GX, Perkin Elmer, USA). The images were taken from the same abdominal region of each rat. To observe visceral fat more clearly, 2D grayscale image slices were reconstructed into 3D images. The visceral fat volume and density was analyzed using Analyze 12.0 software (Analyze Direct, Overland Park, KS, USA) in a blinded manner and the visceral fat weight was calculated.”

Keywords
Blood lead level, Lead exposure, Fatty liver disease, Gut microbiota

Author Affiliation(s)
Shanghai JiaoTong University School of Medicine, Shanghai, China

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