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Childhood stress, serotonin transporter gene and brain structures in major depression

Frodl T, Reinhold E, Koutsouleris N, Donohoe G, Bondy B, Reiser M, Möller HJ, Meisenzahl EM. Childhood stress, serotonin transporter gene and brain structures in major depression. Neuropsychopharmacology. May 2010;35(6):1383-1390.

Full Text – Open Access

Publication Date
May 2010

How Analyze was Used
“The commercial software package Analyze was used (ANALYZE …) for further image processing, with size reduction from 16 to 8 bit and transformation to a uniform matrix of 256 × 256 on 192 slices of 1.0-mm slice thickness.”

Keywords
Adolescent
Adult
Aged
Brain/growth & development/pathology/physiopathology
Brain Chemistry/genetics
Child
DNA Mutational Analysis
Depressive Disorder, Major/genetics/pathology/physiopathology
Female
Gene Frequency
Genetic Predisposition to Disease/genetics
Genetic Testing
Genotype
Hippocampus/growth & development/pathology/physiopathology
Humans
Magnetic Resonance Imaging (MRI)
Male
Middle Aged
Polymorphism, Genetic/genetics
Prefrontal Cortex/growth & development/pathology/physiopathology
Serotonin Plasma Membrane Transport Proteins/genetics
Stress, Psychological/genetics/pathology/physiopathology
Young Adult

Author Affiliation(s)
Department of Psychiatry, Institute of Neuroscience, Trinity College, Dublin, Ireland. (TF, ER, GD)

Department of Psychiatry, Ludwig-Maximilians-University, Munich, Germany. (TF, ER, NK, BB, H-JM, EMM)

Department of Radiology, Ludwig-Maximilians-University, Munich, Germany. (MR)

ID# 1054

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