AnalyzeDirect Megan B. Kuhn et al. C3a-C3aR signaling is a novel modulator of skeletal homeostasis Bone Reports.
Publication Date
February 16, 2023
How Analyze was Used
“Calibrated three-dimensional images were reconstructed. The software Analyze 12.0 Bone Microarchitecture Analysis (AnalyzeDirect) was utilized for trabecular bone at the distal femur and cortical bone at the femoral mid-diaphysis. Trabecular bone was evaluated in axial CT sections starting at 300 μm proximal to the distal growth plate and extending 1000 μm proximally. Cortical bone was assessed in transverse CT slices in a 1000um segment of the mid-diaphysis. A fixed threshold of 1750 Hounsfield units discerned mineralized tissue.”
Keywords
Osteoimmunology, Complement, Osteoblast, Osteoclast
Author Affiliation(s)
Medical University of South Carolina, Charleston, South Carolina, USA
