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Booth T, Bastin ME, Penke L, Maniega SM, Murray C, Royle NA, Gow AJ, Corley J, Henderson RD, Hernández M del C, Starr JM, Wardlaw JM, Deary IJ. Brain white matter tract integrity and cognitive abilities in community-dwelling older people: the Lothian Birth Cohort, 1936. Neuropsychology. September 2013;27(5):595-607.

Full Text – Open Access

Publication Date
September 2013

How Analyze was Used
“[To]… distinguish hyper- and hypointense areas of cerebromalacea, due to old cortical or subcortical infarcts or lacunes, from white matter lesions and CSF, respectively, these areas were masked out from the respective binary masks by thresholding the FLAIR sequence using a region-growing algorithm from Analyze, Version 10.0 (see https://analyzedirect.com/Analyze).”

Keywords
Aged
Aging/pathology/physiology/psychology
Brain/pathology/physiology
Cognition/physiology
Cohort Studies
Diffusion Tensor Imaging
Humans
Memory/physiology
Nerve Fibers/pathology
Scotland

Author Affiliation(s)
Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, Scotland. (TB, MEB, LP, SMM, NAR, AJG, MCVH, JMS, JMW, IJD)

Department of Psychology, University of Edinburgh, Edinburgh, Scotland. (TB, LP, CM, JC, RDH, IJD)

Brain Research Imaging Centre, Division of Neuroimaging Sciences, University of Edinburgh. (MEB, SMM, NAR, MCVH, JMW)

Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE) Collaboration. (MEB, LP, SMM, NAR, MCVH, JMW)

Division of Neuroimaging Sciences, University of Edinburgh, Edinburgh, Scotland. (SMM, NAR, MCVH, JMW)

Psychology, School of Life Sciences, Heriot-Watt University, Edinburgh, Scotland. (AJG)

Geriatric Medicine Unit, University of Edinburgh, Edinburgh, Scotland. (JMS)

ID# 429

Tags: Aged, Aging/pathology/physiology/psychology, Brain/pathology/physiology, Cognition/physiology, Cohort Studies, Diffusion Tensor Imaging, Humans, Memory/physiology, Nerve Fibers/pathology, Scotland