AnalyzeDirect Valdés Hernández MC, Booth T, Murray C, Gow AJ, Penke L, Morris Z, Maniega SM, Royle NA, Aribisala BS, Bastin ME, Starr JM, Deary IJ, Wardlaw JM. Brain white matter damage in aging and cognitive ability in youth and older age. Neurobiol Aging. December 2013;34(12):2740-2747.
Full Text – Open Access
Publication Date
December 2013
How Analyze was Used
“Neuroradiological experts identified…infarcts according to established diagnostic criteria as wedge-shaped or rounded lesions, conforming to a vascular territory, with tissue atrophy and signal characteristics consistent with malacic change. Infarcts, defined as above, were separated from WMH [white matter hyperintensities] manually by thresholding the FLAIR sequences using a region-growing algorithm from Analyze 10.0 (https://analyzedirect.com/Analyze/).”
Keywords
Aged
Aging/pathology/physiology/psychology
Cerebral Cortex/pathology/physiopathology
Cerebrovascular Disease/stroke
Child
Child Psychology
Cognition
Cognition Disorders/etiology/pathology/psychology
Cognitive Aging
Dementia
Female
Humans
Intelligence Tests
Magnetic Resonance Imaging (MRI)
Male
Risk Factors
White Matter Hyperintensities
Author Affiliation(s)
Brain Research Imaging Centre, Department of Clinical Neurosciences, University of Edinburgh, Edinburgh, UK. (MCVH, ZM, SMM, NAR, MEB, JMW)
Department of Psychology, University of Edinburgh, Edinburgh, UK. (MCVH, TB, CM LP, IJD)
Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, UK. (TB, LP, SMM, NAR, MEB, JMS, IJD, JMW)
Department of Geriatric Medicine, University of Edinburgh, Edinburgh, UK. (JMS)
Department of Psychology, School of Life Sciences, Heriot-Watt University, Edinburgh, UK. (AJG)
Department of Computer Science, Lagos State University, Lagos, Nigeria. (BSA)
ID# 209
Tags: Aged, Aging/pathology/physiology/psychology, Cerebral Cortex/pathology/physiopathology, Cerebrovascular Disease/stroke, Child, Child Psychology, Cognition, Cognition Disorders/etiology/pathology/psychology, Cognitive Aging, Dementia, Female, Humans, Intelligence Tests, Magnetic Resonance Imaging (MRI), Male, Risk Factors, White Matter Hyperintensities