AnalyzeDirect Cho SY, Gage KL, Mease RC, Senthamizhchelvan S, Holt DP, Jeffrey-Kwanisai A, Endres CJ, Dannals RF, Sgouros G, Lodge M, Eisenberger MA, Rodriguez R, Carducci MA, Rojas C, Slusher BS, Kozikowski AP, Pomper MG. Biodistribution, tumor detection, and radiation dosimetry of 18F-DCFBC, a low-molecular-weight inhibitor of prostate-specific membrane antigen, in patients with metastatic prostate cancer. J Nucl Med. December 2012;53(12):1883-1891.
Full Text – Open Access
Publication Date
December 2012
How Analyze was Used
“Analyze 10.0…was used to draw source organ contours on the CT scans with the acquired PET images as a guide.”
Keywords
Aged
Aged, 80 and over
Antigens, Surface
Biological Transport
Cysteine/analogs & derivatives/chemistry/diagnostic use/pharmacokinetics/pharmacology
Glutamate Carboxypeptidase II/antagonists & inhibitors
Humans
Male
Middle Aged
Molecular Weight
Neoplasm Metastasis
Positron-Emission Tomography (PET)
Prostatic Neoplasms/metabolism/pathology/radionuclide imaging
Protease Inhibitors/chemistry/diagnostic use/pharmacokinetics/pharmacology
Radiometry
Tissue Distribution
Author Affiliation(s)
Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, MD, US. (SYC, KLG, RCM, SS, DPH, AJK, CJE, RFD, GS, ML, MGP)
Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, US. (SYC, RCM, MAE, RR, MGP)
Brady Urological Institute, Johns Hopkins University, Baltimore, MD, US. (RR, MAC)
Brain Sciences Institute of Johns Hopkins University School of Medicine, Johns Hopkins University, Baltimore, MD, US. (CR, BSS)
Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago College of Pharmacy, Chicago, UL, US. (APK)
ID# 576
Tags: Aged, Aged_80 and over, Biological Transport, Cysteine/analogs & derivatives/chemistry/diagnostic use/pharmacokinetics/pharmacology, Glutamate Carboxypeptidase II/antagonists & inhibitors, Humans, Male, Middle Aged, Molecular Weight, Neoplasm Metastasis, Positron Emission Tomography (PET), Prostatic Neoplasms/metabolism/pathology/radionuclide imaging, Protease Inhibitors/chemistry/diagnostic use/pharmacokinetics/pharmacology, Radiometry, Surface Antigens, Tissue Distribution