Analyze Publications Database

Basal ganglia shape alterations in bipolar disorder

Hwang J, Lyoo IK, Dager SR, Friedman SD, Oh JS, Lee JY, Kim SJ, Dunner DL, Renshaw PF. Basal ganglia shape alterations in bipolar disorder. Am J Psychiatry. February 2006;163(2):276-285.

Full Text – Open Access

Publication Date
February 2006

How Analyze was Used
“All acquired spoiled gradient-recall acquisition volumes were realigned so that the anterior-posterior axis of the brain was parallel to the intercommissural line and the other two axes were aligned along the interhemispheric fissure. T1 images of the caudate heads and putamen were segmented manually by using the guidelines of the Iowa Mental Health Clinical Research Center (http://iowa mhcrc.psychiatry.uiowa.edu/mhcrc/IPLpages/altTracing.htm). These procedures were performed with Analyze 5.0 image visualization and processing software.”

Keywords
Adult
Antipsychotic Agents/pharmacology/therapeutic use
Basal Ganglia/anatomy & histology/drug effects
Bipolar Disorder/diagnosis/drug therapy
Brain Mapping/methods
Caudate Nucleus/anatomy & histology/drug effects
Corpus Striatum/anatomy & histology/drug effects
Female
Humans
Imaging, Three-Dimensional/methods
Lithium/pharmacology/therapeutic use
Magnetic Resonance Imaging (MRI)/methods/statistics & numerical data
Male
Putamen/anatomy & histology/drug effects

Author Affiliation(s)
Department of Psychiatry, Seoul National University Hospital, 28 Yongon-dong, Chongno-gu, Seoul 110-744, South Korea.

ID# 1835

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