AnalyzeDirect Zhu XY, Rodriguez-Porcel M, Bentley MD, Chade AR, Sica V, Napoli C, Caplice N, Ritman EL, Lerman A, Lerman LO. Antioxidant intervention attenuates myocardial neovascularization in hypercholesterolemia. Circulation. May 2004;109(17):2109-2115.
Full Text – Open Access
Publication Date
May 2004
How Analyze was Used
“Images analysis was performed with the Analyze software package.”
Keywords
Animals
Antioxidants/administration & dosage/therapeutic use
Arteriosclerosis/etiology
Ascorbic Acid/administration & dosage/therapeutic use
Cardiotonic Agents/administration & dosage/therapeutic use
Coronary Circulation/drug effects
Diet, Atherogenic
Dinoprost/blood
Enzyme Induction/drug effects
Female
Gene Expression Profiling
Gene Expression Regulation/drug effects
Heart/radiography
Hypercholesterolemia/complications/drug therapy
Hypoxia-Inducible Factor 1, alpha Subunit
Imaging, Three-Dimensional
Myocardial Ischemia/etiology/physiopathology
Neovascularization, Pathologic/drug therapy/prevention & control
Oxidative Stress/drug effects
Superoxide Dismutase/biosynthesis/genetics
Swine
Tomography, X-Ray Computed
Transcription Factors/biosynthesis/genetics
Tyrosine/analogs & derivatives/biosynthesis
Vascular Endothelial Growth Factor A/biosynthesis/genetics
Vitamin E/administration & dosage/therapeutic use
Author Affiliation(s)
Department of Internal Medicine, Division of Hypertension, Mayo Clinic, Rochester, MN, US. (XYZ, ARC, LOL)
Department of Internal Medicine, Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, US. (MRP, NC, AL, LOL)
Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, US. (ERL)
Department of Biological Sciences, Minnesota State University, Mankato, MN, US. (MDB)
Departments of Clinical Pathology and Medicine, University of Naples, Italy. (VS, CN)
Department of Cardiology, Xin-hua Hospital, Shanghai, China. (XYZ)
ID# 2203
Tags: Animals, Antioxidants/administration & dosage/therapeutic use, Arteriosclerosis/etiology, Ascorbic Acid/administration & dosage/therapeutic use, Atherogenic Diet, Cardiotonic Agents/administration & dosage/therapeutic use, Coronary Circulation/drug effects, Dinoprost/blood, Enzyme Induction/drug effects, Female, Gene Expression Profiling, Gene Expression Regulation/drug effects, Heart/radiography, Hypercholesterolemia/complications/drug therapy, Hypoxia-Inducible Factor 1_alpha Subunit, Myocardial Ischemia/etiology/physiopathology, Oxidative Stress/drug effects, Pathologic Neovascularization/drug therapy/prevention & control, Superoxide Dismutase/biosynthesis/genetics, Swine, Three-Dimensional Imaging, Transcription Factors/biosynthesis/genetics, Tyrosine/analogs & derivatives/biosynthesis, Vascular Endothelial Growth Factor A/biosynthesis/genetics, Vitamin E/administration & dosage/therapeutic use, X-Ray Computed Tomography