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Anatomic changes in Schlemm’s canal and collector channels in normal and primary open-angle glaucoma eyes using low and high perfusion pressures

Hann CR, Vercnocke AJ, Bentley MD, Jorgensen SM, Fautsch MP. Anatomic changes in Schlemm’s canal and collector channels in normal and primary open-angle glaucoma eyes using low and high perfusion pressures. Invest Ophthalmol Vis Sci. September 2014;55(9):5834-5841.

Publication Date
September 2014

How Analyze was Used
“Eyes were perfusion fixed at like pressures, dissected into quadrants, embedded in Epon Araldite, and scanned by three-dimensional micro-computed tomography (3D micro-CT). Schlemm’s canal volume, CC orifice area, diameter, and number were measured using ANALYZE software.”

Keywords
Aged
Aged, 80 and over
Female
Glaucoma, Open-Angle/physiopathology
Humans
Intraocular Pressure/physiology
Male
Middle Aged
Trabecular Meshwork/anatomy & histology/pathology

Author Affiliation(s)
Department of Ophthalmology, Mayo Clinic, Rochester, MN, US. (CRH, MPF)

Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, US. (AJV, SMJ)

Department of Biological Sciences, Minnesota State University, Mankato, MN, US. (MDB)

ID# 1197

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