AnalyzeDirect Kenny LM, Contractor KB, Stebbing J, Al-Nahhas A, Palmieri C, Shousha S, Coombes RC, Aboagye EO. Altered tissue 3′-deoxy-3′-[18F]fluorothymidine pharmacokinetics in human breast cancer following capecitabine treatment detected by positron emission tomography. Clin Cancer Res. November 2009;15(21):6649-6657.
Full Text – Open Access
Publication Date
November 2009
How Analyze was Used
“Image analysis was carried out using analysis software (Analyze Version 7 …) as previously reported [Kenny et al. 2005] to obtain time-activity curves.”
Keywords
Antimetabolites, Antineoplastic/pharmacology
Breast Neoplasms/blood supply/metabolism/radionuclide imaging
Deoxycytidine/analogs & derivatives/pharmacology
Dideoxynucleosides/pharmacokinetics
Fluorouracil/analogs & derivatives/pharmacology
Humans
Positron-Emission Tomography (PET)
Regional Blood Flow
Thymidylate Synthase/antagonists & inhibitors
Author Affiliation(s)
Department of Oncology, Imperial College London, London, UK. (LMK, KBC, JS, CP, RCC, EOA)
Department of Nuclear Medicine, Imperial College Healthcare NHS Trust, London, UK. (AAN)
Department of Histopathology, Charing Cross Hospital, Imperial College Healthcare NHS Trust, London, UK. (SS)
ID# 1358
Tags: Antineoplastic Antimetabolites/pharmacology, Breast Neoplasms/blood supply/metabolism/radionuclide imaging, Deoxycytidine/analogs & derivatives/pharmacology, Dideoxynucleosides/pharmacokinetics, Fluorouracil/analogs & derivatives/pharmacology, Humans, Positron Emission Tomography (PET), Regional Blood Flow, Thymidylate Synthase/antagonists & inhibitors