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Addition of endothelial progenitor cells to renal revascularization restores medullary tubular oxygen consumption in swine renal artery stenosis

Ebrahimi B, Li Z, Eirin A, Zhu XY, Textor SC, Lerman LO. Addition of endothelial progenitor cells to renal revascularization restores medullary tubular oxygen consumption in swine renal artery stenosis. Am J Physiol Renal Physiol. June 2012;302(11):F1478-1485.

Full Text – Open Access

Publication Date
June 2012

How Analyze was Used
“Micro-CT images were displayed as three-dimensional volume presentations of the medullary microvasculature. Using Analyze, cross-sectional slabs of medullary regions were selected below the level of the arcuate arteries that were observed in several planes. Mean diameter, tortuosity, as well as microvascular density (100μm) were calculated.”

Keywords
Animals
Blood Volume/physiology
Endothelial Cells/physiology/transplantation
Female
Fibrosis
Hematopoietic Stem Cell Transplantation
Hypoxia-Inducible Factor 1, alpha Subunit/biosynthesis
Image Processing, Computer-Assisted
Kidney/pathology
Kidney Medulla/metabolism/pathology
Kidney Tubules/metabolism/pathology
Magnetic Resonance Imaging
Microvessels/pathology
Oxygen/blood
Oxygen Consumption/physiology
Proteinuria/metabolism
Renal Artery Obstruction/metabolism/pathology
Renal Circulation/physiology
Swine
Tomography, X-Ray Computed
Vascular Endothelial Growth Factor A/biosynthesis

Author Affiliation(s)
Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, US. (BE, ZL, AE, XYZ, SCT, LOL)

Division of Vascular Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China. (ZL)

ID# 536

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