AnalyzeDirect Hammers A, Koepp MJ, Hurlemann R, Thom M, Richardson MP, Brooks DJ, Duncan JS. Abnormalities of grey and white matter [11C]flumazenil binding in temporal lobe epilepsy with normal MRI. Brain. October 2002;125(Pt 10):2257-2271.
Full Text – Open Access
Publication Date
October 2002
How Analyze was Used
“In order to demonstrate the effect size, quantitative region‐of‐interest analyses were performed on non‐normalized parametric images in the ipsilateral TLWM. An average of 2235 mm3 was sampled with circular regions of interest, using Analyze AVW software (Robb and Hanson, 1991) in all 15 patients with a unilateral focus, and in corresponding areas in all 21 controls.”
Keywords
Adolescent
Adult
Brain/metabolism/pathology/radionuclide imaging
Carbon Radioisotopes/diagnostic use/metabolism
Epilepsy, Temporal Lobe/metabolism/pathology/radionuclide imaging
Female
Flumazenil/diagnostic use/metabolism
Humans
Linear Models
Magnetic Resonance Imaging (MRI)/statistics & numerical data
Male
Middle Aged
Receptors, GABA-A/metabolism
Tomography, Emission-Computed/statistics & numerical data
Author Affiliation(s)
MRC Clinical Sciences Centre and Division of Neuroscience, Faculty of Medicine, Imperial College, London, UK. (AH, MJK, MPR, DJB, JSD)
Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, London, UK. (AH, MJK, RH, MT, MPR, JSD)
National Society for Epilepsy MRI Unit, Chalfont St Peter, UK. (AH, MJK, MPR, JSD)
ID# 2609
Tags: Adolescent, Adult, Brain/metabolism/pathology/radionuclide imaging, Carbon Radioisotopes/diagnostic use/metabolism, Emission-Computed Tomography/statistics & numerical data, Female, Flumazenil/diagnostic use/metabolism, GABA-A Receptors/metabolism, Humans, Linear Models, Magnetic Resonance Imaging (MRI)/statistics & numerical data, Male, Middle Aged, Temporal Lobe Epilepsy/metabolism/pathology/radionuclide imaging