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A randomized phase 1b cross-over study of safety of low-dose pioglitazone for treatment of autosomal dominant polycystic kidney disease

Bonnie Blazer-Yost et al. A randomized phase 1b cross-over study of safety of low-dose pioglitazone for treatment of autosomal dominant polycystic kidney disease Clinical Kidney Journal.

Publication Date
January 26, 2021

How Analyze was Used
“Kidneys or liver volumes were measured from coronal T1-weighted images from MR or axial CT images, using a stereological method with Analyze software (AnalyzeDirect, Overland Park, KS, USA). Initial measurements for screening were done by one of three available radiologists, but actual study results were read by a single radiologist blinded to study intervention.”

Keywords
Anti-hypertensive, Crossover design, MRI, PPARγ, Agonists, Total kidney volume

Author Affiliation(s)
Indiana University-Purdue University at Indianapolis, Indianapolis, Indiana, USA.

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