Li Zhou et al. A Quality by Design (QbD) Project of Human Dermal Fibroblast and its Therapeutic Effects on Managing Degenerative Intervertebral Disc Fibrosis in Rabbit and Cynomolgus Monkey Frontiers of Bioscience Landmark Edition
Publication Date
March 12, 2025
How Analyze was Used
“The gray value, representing the intervertebral disc’s water content, was derived from the MRI index and measured using Analyze 14.0 software (AnalyzeDirect, Overland Park, KS, USA). All images were measured by three independent observers unaware of the sample, and the average of their assessments was recorded.”
Keywords
Lumbar/intervertebral disc (IVD), Human dermal fibroblasts (HDFs), Intervertebral disc degeneration (IVDD), Low back pain, Cell therapy
Author Affiliation(s)
Shanghai Jiao Tong University School of Medicine, Shanghai, China