Analyze Publications Database

A longitudinal study of hippocampal volume, cortisol levels, and cognition in older depressed subjects

O’Brien JT, Lloyd A, McKeith I, Gholkar A, Ferrier N. A longitudinal study of hippocampal volume, cortisol levels, and cognition in older depressed subjects. Am J Psychiatry. November 2004;161(11):2081-2090.

Publication Date
November 2004

How Analyze was Used
“Images were transferred to a Sun Ultra 10 work station … running Solaris 2.7 and analyzed by a single operator (who was blind to diagnosis) using the commercially available software package AnalyzeAVW-3.0 (AnayzeDirect.com, Lenexa, Kan.).”

Keywords
Age Factors
Aged
Area Under Curve
Circadian Rhythm/physiology
Cognition Disorders/diagnosis
Depressive Disorder, Major/diagnosis/psychology
Female
Geriatric Assessment
Hippocampus/anatomy & histology
Humans
Hydrocortisone/analysis/blood
Longitudinal Studies
Magnetic Resonance Imaging (MRI)
Male
Middle Aged
Neuropsychological Tests
Psychiatric Status Rating Scales
Saliva/chemistry

Author Affiliation(s)
Wolfson Research Centre, Institute for Ageing and Health, Newcastle General Hospital, Westgate Road, Newcastle Upon Tyne NE4 6BE, UK.

ID# 2355

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