AnalyzeDirect Randall T. Loder et al. A Healed Intertrochanteric Femur Fracture, Shoulder, and Rib Fractures in an Ancient Nubian Female: An Osteoarchaeological Perspective The Scientific World Journal.
Publication Date
February 12, 2024
How Analyze was Used
“The 3D vertebral scans were analyzed using Analyze 12.0 software (BIR, Mayo Clinic). Scans were imported and manually edited to include only the middle one-third section of the trabecular bone of the vertebral body, excluding the cortical bone, effectively manually determining the region of interest (ROI), which refers to a specific region of the image data defined and selected for a specific analysis or purpose. Areas of the bone with mineral deposits were manually sectioned out or removed by thresholding so that they would not interfere with bone microarchitecture output. Edited scans were then analyzed using the Bone Microarchitecture Analysis (BMA) app within the software to assess the standard American Society for Bone and Mineral Research (ASBMR) microarchitecture measures [58]. A calibration phantom was utilized to calibrate the scans to generate TMD scores. As the calculation for trabecular BMD (TMD) in the Analyze software algorithm is designed for use in living specimens rather than archaeological samples in which there is a degree of diagenesis, the calibrated scores for each individual may not reflect the true mineral density scores in mg HA (hydroxyapatite)/cm3 for comparison with fresh bone.”
Keywords
Intertrochanteric, Femur Fractures, Shoulder Fractures, Rib Fractures, Ancient Nubian, Osteoarchaeology
Author Affiliation(s)
Indiana University School of Medicine, Indianapolis, Indiana, USA
