Analyze Publications Database

Enhancement of intragastric acid stability of a fat emulsion meal delays gastric emptying and increases cholecystokinin release and gallbladder contraction

Marciani L, Wickham M, Singh G, Bush D, Pick B, Cox E, Fillery-Travis A, Faulks R, Marsden C, Gowland PA, Spiller RC. Enhancement of intragastric acid stability of a fat emulsion meal delays gastric emptying and increases cholecystokinin release and gallbladder contraction. Am J Physiol Gastrointest Liver Physiol. June 2007;292(6):G1607-1613.

Full Text – Open Access

Publication Date
June 2007

How Analyze was Used
“Measurements of the volume of the gastric contents were carried out by manually tracing a region of interest around the meal within the stomach on each image slice with Analyze software.”

Keywords
Administration, Oral
Adult
Cholecystokinin/blood
Dietary Fats, Unsaturated/administration & dosage/pharmacokinetics/pharmacology
Emulsifying Agents/chemistry
Emulsions
Gallbladder Emptying/drug effects
Gastric Acid/metabolism
Gastric Emptying/drug effects
Hexoses/chemistry
Humans
Magnetic Resonance Imaging (MRI)
Male
Plant Oils/administration & dosage/pharmacokinetics/pharmacology
Polysorbates/chemistry
Postprandial Period
Satiety Response/drug effects
Stomach/drug effects/metabolism

Author Affiliation(s)
Wolfson Digestive Diseases Centre, Queen’s Medical Centre University Hospital, Nottingham, UK. (LM, RCS)

Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, UK. (LM, EC, PAG)

Institute of Food Research, Norwich, Norfolk, UK. (MW, AFT, RF)

School of Biomedical Sciences, University of Nottingham, Nottingham, UK. (GS, CM)

Division of Surgery, Queen’s Medical Centre University Hospital, Nottingham, UK. (DB, BP)

ID# 1764

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