AnalyzeDirect Edison P, Archer HA, Gerhard A, Hinz R, Pavese N, Turkheimer FE, Hammers A, Tai YF, Fox N, Kennedy A, Rossor M, Brooks DJ. Microglia, amyloid, and cognition in Alzheimer’s disease: an [11C](R)PK11195-PET and [11C]PIB-PET study. Neurobiol Dis. December 2008;32(3):412-419.
Publication Date
December 2008
How Analyze was Used
“Cerebellar tracer uptake was then calculated by sampling the 60–90 minute image using the cerebellar gray matter object map (see below) in Analyze AVW 6.1.”
Keywords
Aged
Alzheimer Disease/physiopathology/psychology/radionuclide imaging
Amyloid/analysis
Aniline Compounds/diagnostic use
Carbon Radioisotopes/diagnostic use
Cerebral Cortex/chemistry/physiopathology/radionuclide imaging
Cluster Analysis
Cognition
Female
Humans
Isoquinolines/diagnostic use
Magnetic Resonance Imaging (MRI)
Male
Microglia/physiology
Middle Aged
Positron-Emission Tomography (PET)
Thiazoles/diagnostic use
Author Affiliation(s)
MRC Clinical Sciences Centre and Division of Neuroscience, Cyclotron Building Hammersmith Hospital, Imperial College London, W12 0NN, UK. (PE, AG, NP, FET, AH, YFT, AK, MR, DJB)
Dementia Research Centre, UCL, Institute of Neurology, Mainz, Germany. (HAA, NF, MR)
Hammersmith Imanet, GE Healthcare, Mainz, Germany. (RH, DJB)
Wolfson Molecular Imaging Centre, The University of Manchester, Manchester, UK. (AG, RH)
ID# 1617
Tags: Aged, Alzheimer Disease/physiopathology/psychology/radionuclide imaging, Amyloid/analysis, Aniline Compounds/diagnostic use, Carbon Radioisotopes/diagnostic use, Cerebral Cortex/chemistry/physiopathology/radionuclide imaging, Cluster Analysis, Cognition, Female, Humans, Isoquinolines/diagnostic use, Magnetic Resonance Imaging (MRI), Male, Microglia/physiology, Middle Aged, Positron Emission Tomography (PET), Thiazoles/diagnostic use