AnalyzeDirect Zobel A, Jessen F, von Widdern O, Schuhmacher A, Höfels S, Metten M, Rietschel M, Scheef L, Block W, Becker T, Schild HH, Maier W, Schwab SG. Unipolar depression and hippocampal volume: impact of DNA sequence variants of the glucocorticoid receptor gene. Am J Med Genet B Neuropsychiatr Genet. September 2008;147b(6):836-843.
Publication Date
September 2008
How Analyze was Used
“Scanning was performed on a Philips 1.5T Achieva whole body system with a 3D FFE sequence (TE/TR/FLIP: 15/3.6 msec/30°) with 140 slices and a resolution of 1 × 1 × 1 mm3 . Data were converted to the analyze-format and manual volumetry was performed with Analyze 7.0.”
Keywords
Adolescent
Adult
Aged
Amygdala/pathology
Case-Control Studies
Chromosomes, Human, Pair 5
DNA Mutational Analysis
Depressive Disorder/genetics/pathology/radiography
Female
Gene Frequency
Hippocampus/pathology/radiography
Humans
Linkage Disequilibrium
Male
Middle Aged
Organ Size/genetics
Polymorphism, Single Nucleotide/physiology
Protein Isoforms/genetics
Receptors, Glucocorticoid/genetics
Author Affiliation(s)
Department of Psychiatry, University of Bonn, Bonn, Germany. (AZ, FJ, OW, AS, SH, MM, MR, WM, SGS)
Central Institute of Mental Health, Division of Genetic Epidemiology in Psychiatry, Mannheim, University of Heidelberg, Heidelberg. (MR)
Department of Radiology, University of Bonn, Bonn, Germany. (LS, WB, HHS)
Institute for Medical Biometry, Informatics and Epidemiology, University of Bonn, Bonn, Germany. (TB)
Western Australian Institute for Medical Research and School of Psychiatry and Clinical Neurosciences, University of Western Australia, Perth, Western Australia, Australia. (SGS)
ID# 1545
Tags: Adolescent, Adult, Aged, Amygdala/pathology, Case-Control Studies, Depressive Disorder/genetics/pathology/radiography, DNA Mutational Analysis, Female, Gene Frequency, Glucocorticoid Receptors/genetics, Hippocampus/pathology/radiography, Human Chromosomes_Pair 5, Humans, Linkage Disequilibrium, Male, Middle Aged, Organ Size/genetics, Protein Isoforms/genetics, Single Nucleotide Polymorphism/physiology