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Chen R, Nishimura MC, Kharbanda S, Peale F, Deng Y, Daemen A, Forrest WF, Kwong M, Hedehus M, Hatzivassiliou G, Friedman LS, Phillips HS. Hominoid-specific enzyme GLUD2 promotes growth of IDH1R132H glioma. Proc Natl Acad Sci U S A. September 2014;111(39):14217-14222.

Full Text – Open Access*

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Publication Date
September 2014

How Analyze was Used
“For determination of tumor volumes, the area of hyperintensity on the T2-weighted images was outlined semiautomatically using the Auto Trace tool in Analyze 11.0 (AnalyzeDirect), with subsequent manual editing to exclude ventricles.”

Keywords
Astrocytoma
Oligodendroglioma
Tumor Metabolism

Author Affiliation(s)
Department of Translational Oncology, Genentech Inc., South San Francisco, CA 94080, US. (RC, MCN, SK, MK, GH, LSF, HSP)

Department of Pathology, Genentech Inc., South San Francisco, CA 94080, US. (FP)

Department of Drug Metabolism and Pharmacokinetics, Genentech Inc., South San Francisco, CA 94080, US. (YD)

Department of Bioinformatics and Computational Biology, Genentech Inc., South San Francisco, CA 94080, US. (AD, WFF)

Department of Biomedical Imaging, Genentech Inc., South San Francisco, CA 94080, US. (MH)

ID# 1172

Tags: Astrocytoma, Oligodendroglioma, Tumor Metabolism