Frodl T, Reinhold E, Koutsouleris N, Donohoe G, Bondy B, Reiser M, Möller HJ, Meisenzahl EM. Childhood stress, serotonin transporter gene and brain structures in major depression. Neuropsychopharmacology. May 2010;35(6):1383-1390.
Full Text – Open Access
Publication Date
May 2010
How Analyze was Used
“The commercial software package Analyze was used (ANALYZE …) for further image processing, with size reduction from 16 to 8 bit and transformation to a uniform matrix of 256 × 256 on 192 slices of 1.0-mm slice thickness.”
Keywords
Adolescent
Adult
Aged
Brain/growth & development/pathology/physiopathology
Brain Chemistry/genetics
Child
DNA Mutational Analysis
Depressive Disorder, Major/genetics/pathology/physiopathology
Female
Gene Frequency
Genetic Predisposition to Disease/genetics
Genetic Testing
Genotype
Hippocampus/growth & development/pathology/physiopathology
Humans
Magnetic Resonance Imaging (MRI)
Male
Middle Aged
Polymorphism, Genetic/genetics
Prefrontal Cortex/growth & development/pathology/physiopathology
Serotonin Plasma Membrane Transport Proteins/genetics
Stress, Psychological/genetics/pathology/physiopathology
Young Adult
Author Affiliation(s)
Department of Psychiatry, Institute of Neuroscience, Trinity College, Dublin, Ireland. (TF, ER, GD)
Department of Psychiatry, Ludwig-Maximilians-University, Munich, Germany. (TF, ER, NK, BB, H-JM, EMM)
Department of Radiology, Ludwig-Maximilians-University, Munich, Germany. (MR)
ID# 1054
Tags: Adolescent, Adult, Aged, Brain Chemistry/genetics, Brain/growth & development/pathology/physiopathology, Child, DNA Mutational Analysis, Female, Gene Frequency, Genetic Polymorphism/genetics, Genetic Predisposition to Disease/genetics, Genetic Testing, Genotype, Hippocampus/growth & development/pathology/physiopathology, Humans, Magnetic Resonance Imaging (MRI), Major Depressive Disorder/genetics/pathology/physiopathology, Male, Middle Aged, Prefrontal Cortex/growth & development/pathology/physiopathology, Psychological Stress/genetics/pathology/physiopathology, Serotonin Plasma Membrane Transport Proteins/genetics, Young Adult