Analyze Publications Database

Pontine-to-midbrain ratio indexes ocular-motor function and illness stage in adult Niemann-Pick disease type C

Walterfang M, Macfarlane MD, Looi JCL, Abel L, Bowman E, Fahey MC, Desmond P, Velakoulis D. Pontine-to-midbrain ratio indexes ocular-motor function and illness stage in adult Niemann-Pick disease type C. Eur J Neurol. March 2012;19(3):462-467.

Publication Date
March 2012

How Analyze was Used
“Quantification of mesencephalic size was performed by measuring the area of the midbrain and pons in the midsagittal slice for each subject using Analyze 10 software … on a dual-core Apple MacBook Pro, by manual tracing.”

Keywords
Adolescent
Adult
Brain Stem/pathology/physiopathology
Disease Progression
Female
Humans
Image Interpretation, Computer-Assisted
Magnetic Resonance Imaging (MRI)
Male
Middle Aged
Niemann-Pick Disease, Type C/complications/pathology/physiopathology
Saccades/physiology
Young Adult

Author Affiliation(s)
Melbourne Neuropsychiatry Centre, University of Melbourne, Melbourne, Australia. (MW, EB, DV)

Neuropsychiatry Unit, Royal Melbourne Hospital, Melbourne, Australia. (MW, DV)

Research Centre for the Neurosciences of Ageing, Academic Unit of Psychological Medicine, Australian National University Medical School, Canberra, Australia. (MDM, JCLL)

Department of Optometry and Vision Sciences, University of Melbourne, Melbourne, Australia. (LA, EB)

Department of Pediatrics, Monash University, Melbourne, Australia. (MCF)

Department of Radiology, Royal Melbourne Hospital, Melbourne, Australia. (PD)

Department of Radiology, University of Melbourne, Melbourne, Australia. (PD)

ID# 985

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