AnalyzeDirect Murray ME, Vemuri P, Preboske GM, Murphy MC, Schweitzer KJ, Parisi JE, Jack CR, Jr., Dickson DW. A quantitative postmortem MRI design sensitive to white matter hyperintensity differences and their relationship with underlying pathology. J Neuropathol Exp Neurol. December 2012;71(12):1113-1122.
Full Text – Open Access
Publication Date
December 2012
How Analyze was Used
“Five slices were selected from each of the 4 postmortem FLAIRs at the level of the nucleus accumbens, lentiform nucleus, lateral geniculate nucleus, splenium, and primary visual cortex. The software program Analyze…was used to match FLAIR slices and autopsy photographs on a dual-monitor system.”
Keywords
Aged
Aged, 80 and over
Brain/pathology
Female
Humans
Image Processing, Computer-Assisted
Magnetic Resonance Imaging (MRI)
Male
Nerve Fibers, Myelinated/pathology
Postmortem Changes
Author Affiliation(s)
Department of Neuroscience, Mayo Clinic Jacksonville, FL, US. (MEM, DWD)
Department of Radiology, Mayo Clinic Jacksonville, FL, US. (KJS)
Department of Radiology, Mayo Clinic Rochester, MN, US. (PV GMP, MCM, CRJ)
Department of Pathology, Mayo Clinic Rochester, MN, US. (JEP)
ID# 554
Tags: Aged, Aged_80 and over, Brain/pathology, Computer-Assisted Image Processing, Female, Humans, Magnetic Resonance Imaging (MRI), Male, Myelinated Nerve Fibers/pathology, Postmortem Changes